My research interests are focused on the interactions between T lymphocytes, a crucial arm of the immune system, and other arms of the immune system and ways that we can use these interactions to modulate the resultant T cell responses in a clinically useful way. I have studied this in the context of autoimmune process, graft transplantation and during trauma. My current interests involve i) the role of regulatory CD8lo T cells produced in vivo after incomplete antigen stimulation and ii) the role of homeostatic proliferation and apoptosis of T cells in causing a perturbed immune system in models of burn injury.
