Dr. McGraw's research involves understanding the mechanisms of aberrant airway epithelial repair after inhalation injuries. The primary pediatric lung disease studied is bronchiolitis obliterans (BO), a devastating and often progressive fibrotic lung disease characterized by progressive luminal narrowing and obliteration of the small airways, or bronchioles. Despite BO's high morbidity and mortality, very little is known about its pathogenesis, and even less is available in terms of prevention, intervention and treatment.
