My research focuses on understanding the aetiology of Alzheimer's disease (AD). In particular, I focus on the development of cerebral amyloid angiopathy (CAA), the deposition of toxic β-amyloid proteins in the walls of the blood vessels of the AD brain. I am interested in how risk factors for AD, such as ageing and obesity, affect the structure of the blood vessels and their ability to remove β-amyloid from the brain.
